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The staff centered on blocking a protein known as synaptotagmin-2, or Syt2. Syt2 is observed around the floor with the granules made up of mucin. Fusion of such granules With all the mobile membrane is dependent upon Syt2 interacting with proteins inside the mobile membrane.
As a result, blocking the activity of Syt2 must avert unexpected massive mucin launch with out impairing gradual, regular baseline mucin secretion that is needed for airway overall health."
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